We all want to get hired at a major ASAP, so what makes you more qualified than us? What's your background? Are you military looking to build 121 experience before mama D calls? Or are you a fresh ATP with 1500hrs under their belt?
If you really want MSP, I might go for Endeavor. But that's based solely on QOL.
As far as getting to the majors faster, volunteer as much as you can outside of flying. Habitat, pilots for kids, etc. Seems like all the recruiters I've talked to love that stuff.