I commuted internationally for years and I can say it depends on your situation, seniority, schedules. My wife went back home (Europe) to help with her mom.

For 4.5 years I would go back and forth between New York and western Europe. It was the lowest stress commute I ever had. Worst part was the bus ride to and from the airport. All the flights to the States left within a 1.5 hours of each other. First class 90% of the time. Missed 3 times in 4.5 years. First day was normally a deadhead or 1 leg to the overnight.

Got onboard aircraft. Eat my breakfast. Sleep for 5 hours. Watch a movie and go to work.