As someone said earlier, technically it is possible, but practically it is very difficult.

As a line holder, you can use the "48hr period" swap window to trade trips on your line with open time. The issue here is that there are typically not a lot of open trips to swap with, and the ones that are available often have Part 117 limitations. Also, per the contract, you are limited to trading 6 days per bid period in the 48hr window.

Your other option, as a reserve or (especially) a build up holder, is to try to put your 4 "golden" days (consecutive, unassignable, un-junior-mannable days awarded to build up/reserves) together in a row. For example, you could place your June golden days on the last 4 days of the month, and July golden days on the first 4 days of July, thereby getting 8 days off in a row. This would only be possible every two months, obviously. Also, build up requests are just that - requests- and don't necessarily have to be honored.

They have been better lately about trying to honor golden day requests, but obviously not every reserve is going to get Christmas Day off, for example...