The 757-300 is actually easier to fly than the -200, in my view. Longer moment arm from the tail makes control forces lighter for rotation and flare. It seems more speed-stable on approach, which I am chalking up to inertia....it's heavier.
It is great to Hawaii. It can't fly the Atlantic.
The 767-400 is a great plane. I haven't flown the -300 or -200 for comparison, but it has power, range, speed, comfort, and stopping ability. The difference from the uber-Guppies? More thrust, and more wing, than the 767-300.
I think the main gear may have been stretched, too, because the -400s always look a little nose-low on the ramp, compared to -300s. I know that the inability to make it sit higher is a major issue with the 737-stretch and rotations/flares and potential tail-strikes.