If you get bed bugs in your luggage, a little preemptive action will keep them out of your house. First, never put your bag on the hotel bed. You did already? Crap. Well DONT TAKE YOUR BAGS INTO YOUR HOUSE. That right. Leave it in the garage or porch. Take all the clothes out, put them in a bag and dump them straight into the dryer. (Not the bag though.) Run it on as hot as you can get it. Heat kills them. Take a hair dryer on high and basically cook your bag. Pay attention to the corners and any folds. Don't rush it.
Next time you'll do a better job of checking the hotel room before hand!