Proper prior planning. Know your route, your aircraft, and yourself. Along the way, when in IFR or VFR weather you should always be prepared for an abnormality. I would say in a single engine aircraft its a bit more like Slice said, a little paying might not hurt, but you still need to fly the airplane, Pick a direction based on your route, and talk to someone. The basics realy apply in this case. In a twin it becomes a bit more complicated because there are more options and variables. BUT, the basics still apply.
Good Luck