141 training programs generally cost more and have less flexibility than part 61 programs.
In the past, the best (and only in most cases) justification to go 141 was if you had military GI Bill benefits...that would only pay for 141 programs.
Now there is another benefit to 141, reduced minimum flight time to qualify for an ATP (and hence an airline job), referred to as R-ATP. But the catch is that you ONLY get that benefit if enrolled in a two or four year degree program with a school that offers 141 training as part of the degree program. The school has to be approved for R-ATP as well. This probably does not apply to you unless you want to earn another degree. Of course these programs are not cheap...
61 offers best value and flexibility. 141 schools will try to sell you about how airlines prefer 141, blah, blah. Total BS, schools like 141 because they get to charge you MORE but graduate you with LESS total flight time. BTW, the sole criteria for getting a regional job today is total flight time, ie ATP mins. So why pay more for less total time???