It depends. I was in indoc last Mar and the rumor was the ER was being phased out so many ran from it. I knew I wanted the variety in flying and liked the jet so I picked it. A year later I have no regrets. In a few years I might...who knows? In my 6 months flying after OE/TOE, I have held a line twice. I live in base so reserve doesn't bother me. I believe the last road show announced they bought a few more 757s and were also pulling some from the boneyard and would have 15-20 more flying this summer than last. Winter flying slowed down and I sat for 3 weeks at home and barely flew in Jan. Still got paid the reserve amount and had some great family time. I guess I could get displaced, but I haven't even remotely had to worry about that yet.

Bottom line: do your homework and decide based on your situation. I chose aircraft and base and have no regrets. I gave up some seniority for that, but not as much as some would think. I love my situation now and will only know if I made the right decision when I retire. Good luck!