To the OP. Many have left...
After several airline shut downs (including Comair), I left.
I truly miss the 121 world but would never consider going back unless pay and qol improve substantially. I still get to fly a dinky King Air but my qol has shot through the roof. I have more time off, am building an airplane and travelled to Europe 3 time last year. When the airline CEO's get a clue, I would love to jump back in.