Thanks to all for the replies.
From a financial point of view, unless you can work out a deal with an FBO it sounds like it might not really be a viable option. It might be a option every now and then, but certainly not as the primary means of commuting.
I'm also not too keen on putting myself into a situation where I am forced to fly my single engine piston into weather because I planned poorly and didn't have any backup options to get to work.