It depends on the base and how you weight the particular trips for QOL. If you are in NYC and value long Asia, you are out of luck. If you are in ATL and want 6 day Europe with MSP and DTW layovers, life will be good. Seasonal fluctuations impact the bases as well. Last year the ATL 330 was the dedicated MED plane. If you were in the bottom half of the list, DEET became a higher priority than toothpaste and shaving cream when packing.

NYC has mostly 3 day Europe, with occasional 6 day trips through MSP or ATL. Lots of 15:45 trips, with the 6 day 33:00+ trips going senior. The seasonal late ATH trip is a tough commute on the back end, so it is great for a local. The two day LAX is an easy 12 hours for true locals. If you are a 4 hour PA "local", maybe not.

ATL currently has a mix of 3 and 6 day Europe with 3 day trips going senior. Last fall, the bottom half of the list was flying 4 day deep South America.

DTW has the best mix of Asia and Europe.

SEA flys mostly Asia with some CDG and AMS in the mix.

DYODD and scan a few of the bid packs. I'd recommend pulling a few months of each category across various seasons of the year.