Depends on:

1. Background/TT and experience
2. College Degree?
3. Age?
4. Where to you want to be in the future?
5. How much flying to you want to do? (regionals will net 700+ hrs a year whereas Atlas, probably a lot less with lots of deadhead and not that many takeoffs/landings)
6. Are you ok with being gone for 15 plus days (Atlas or any ACMI for that matter)?