Every regional I've ever worked at it's been fairly easy to hold one stretch of five in a row off a month once off reserve and have a bit of seniority. Of course you have to be realistic...you won't be able to do that AND hold wknds off for example.

I'm on a stretch of 10 off in a row and it's a crap schedule month with ground school etc. I usually plan on a stretch of 6-8 off every month...my mini monthly vacation. YMMV...