Back to the original question from the OP; Any night you have to stay up all night after an extended period of off days is going to be tough. Usually it is Monday PM/Tuesday AM due to system form, but it could be any night. As someone else said, you don't hear a lot of complaining, more likely, you'll just experience the quite of two pilots digging deeper into fatigue as they fly towards the end of their duty day. I don't think anyone really enjoys it, but night flying does offer similar advantages to a driver on the roads at the quietest time of the day, little to no traffic!