The ability to fly transcon also allows for greater aircraft utilization meaning the fixed costs are spread out among more flight hours.
The 190 flies about two fewer hours per day than the airbus fleet because of the reduced stage lengths and lack of red eyes it flies.
The CSeries greater range could unlock a lot of smaller transcon markets that don't work with the airbus but still have demand for a red eye flight to New York, Boston, FLL, etc.