Maybe there is no one right or wrong way to make it into an airline job. But you can't argue with experience. A 300 hour pilot really has no business taking 50 people's lives and his company's reputation in his hands. And, BigWammer- I totally understand where you're coming from. When I was a 300 hour CFI, I would have sold my left nut to fly an RJ. But as you gain more experience, you start to realize how woefully unprepared you were. I look back nowadays, and still think I wasn't ready for my first airline gig- even with 1600TT, an ATP and 121 Dispatcher experience.
Get back to us when you've got 2000 hours...
Anyone can fly a plane, anyone can throw switches and run flows....
But CRJ sim and systems classes don't provide you with the ability to make fully informed command decisions in a 121 environment.... that only comes with experience.