Yes, absolutely, if you have a family or other reasons that are important to you. These are just jobs and one legacy (regional, cargo, etc) is quite similar to the next at the end of the day (paychecks not always withstanding, though similar within classification). It took me a long time and a couple of furloughs to figure that out.

And of course something could go wrong, this is life in a deteriorating society. But if you cannot control it you just have to save a little cash and enjoy the ride as best you can.