Obviously self driving modes will only be available on preset routes where the variables are controllable. This is why if you are a truck driver, you're toast, as all the routes are preset. Also, depending on how well self driving cars operate, the regional airline industry is probably toast as well. If I can get in my car at 9pm, and the car drives me all night to my destination while I sleep, that's the way I'm going, as would most Americans.