I applied to 7 that I was interested in. I did 6 interviews and got 7 job offers. (I don't count a 10 min conversation on the phone 30 mins after submitting an application an interview.)
I am very glad I did multiple interviews. If you can afford to give up a couple of weeks or month (not getting a pay check), plan out the interviews and get a good idea of the companies that are out there and be able to distinguish the differences between them you'll be doing yourself a favor. The industry is way different than it used to be. If you have the hours and the ratings you will most likely get hired at any regional you choose.