Single Pilot freight flying without a autopilot in twin Cessnas OR a Turboprop is one of the most challenging type of environments a pilot can fly in. It rates up there with NVG flying or vertical reference in a helicopter in my personal opinion. I found that once I moved into Jets with autopilots and flight guidance systems, I thought that my background of single
Pilot 135/freight made flying a Jet with an autopilot seem relatively easy. I am not sure why UPS/ FEDEX hiring departments do not value that experience, but they should. The 121 carrier I work at did value it on my application many years ago.