I asked my dad if he hand-flys at all (Capt 75/76 at USAIR) and he said most times up to 10,000 feet he does hand fly and performs basic turns and such to see if the airplane is handling normally and no malfunctions/abnormalities in the flight controls....then usually autopilot for cruise and hands flys the landing. Interesting point he brought up that you could miss if you turned on the autopilot right after rotation!