It's not the end, but you're going to have a hard time getting hired. A friend that washed out at TSA had one hell of a time finding work last year. He had 135 minimums but nobody would take him. He intereviewed at a number of 121 carriers and Skyway finally offered him a job 6 months after the wash.
Good luck, study your ass off. If it's too late for that, be honest about it. Regardless of PRIA or not, it could come back to haunt you if you lie.