Very route dependent....have gone on trips with lots of flying, where it was "go, go, go" and some where you have lots of time to spend doing other things. One thing to keep in mind is that you must always rest enough to be safe, and flying mostly single pilot, you don't have anybody to watch you for mistakes, and the paperwork, etc.
First and foremost, remember it is a full time job if you are on the schedule. Yes, home based Captains do get full weeks off at home, when not "on".
My suggestion, find a way to live within your income so you are not spreading yourself too thin, especially when you start. After a few months or a year, maybe you could do some side gigs...but trying to do too much can lead to errors and fatigue. Many freight pilots have lost friends, myself included, that have known people who have tried to do "extra" and made dumb mistakes.... mistakes might result in a "resume writing event" or worse, loss of life.