Pathway is more of a gimmick. Its just an interview.
A genuine flow through agreement is seniority based, meaning you just wait your turn to go to a major airline. Both Unions agree to it. In theory if you get hired at PSA or Envoy that could be the last interview you'll ever have in your life. Just wait and flow to American. The time it takes is the downside; 6 to 10 years depending on who you talk to.
American has the only real flow from what I've read. Gojet is calling their pathway to spirit a "flow" but it's still another interview and there are other things that make it a bad deal. Correct me if I'm wrong but from what I've seen you're more likely to see a flow through agreement to a major from a regional that is 100% owned by that major I.e. American Airlines and PSA, Envoy, Peidmont. The only other majors with wholly owned regionals are Delta - Endeavor and Alsaka - Horizon. United doesn't own any regional just yet but we'll see how that shakes out in the next few years.
Granted I haven't started training yet but if Horizon did have a flow they would be the perfect airline for me.