Chris99 nailed it.

I left NJA for 121 and I would choose to be a Starbucks Barista before I ever have to fly for an operation even remotely similar to NJA. I would not recommend leaving a regional for NJA, in fact guys are leaving NJA for regionals. 1 person who left for a regional was just hired at UAL, and another has an interview with UAL. Both left for CommuteAir.

The schedule as far as days on and days off does look appealing, and 7/7 is nice to know when you are working, and when you are off. I have flown prior 135, 91, 135 single pilot freight and I have worked for some shady operators. I have never worked as hard as I did at NJA. For those 7 days you will be run ragged, and you will be sent home destroyed. I just hit year two pay at my airline, and you would have to work 25 days a month to match that at NJA on 2nd year pay.

For those at a regional who have a weird commute, NJA might be an ok fit for a while but you will get the itch and do everything and anything to leave for 121 again.

Benefits are pretty good but when you compare what benefits costs at an airline versus the DC 401k you get, you will come out in the black all day long. Don't let free health care fool you into taking 30 years of sub par pay and retirement.

NJA does lots of things operationally right though. If a light bulb is burned out, you write it up and that plane goes down, even if they have to send a plane across the country to recover the trip, and although the occasional dispatcher will try to kill you, the operation is very safe. But they will push you to your breaking point on an almost daily basis, and it wouldn't be uncommon to have your schedule change 30 times in a 7 day period, it adds a level of stress and anxiety on top of the long duty days and short overnights.