So far (one month in) it's been pretty good. Best seen to date was the Guest House at Graceland in Memphis. Very cool hotel, location, etc.
Staying across the street from Mall of America is pretty nice at MSP.
And Towneplace Suites in CMH has a really nice breakfast and nice rooms.
Most interesting/quirkiest hotel has to be the Garden Place Hotel in BUF. You'll know what I'm talking about when you go there.