Go find a CFI (preferably a moonlighting airline pilot) and get current on the basics, BFR, stalls, steeps, LDGs, IPC (no need for commercial maneuvers or special LDGs). You probably don't need ME currency, unless you apply to a regional which requires it (if any still do).
Pick a regional. Any regional, any of them will hire you and beg you to start class next Monday. So do your research, because you have a choice to make. Will Fly for Food has interview gouge. Consider a regional where you can upgrade right away (like a few months after IOE), if you're going to be junior, may as well get CA pay and TPIC.
It would be easier on you if you return to the CRJ, that plane will come back quick... especially if you want to upgrade soon. I did a multi-year break from the CRJ and after ground school and about one sim I was checkride ready, we spent the rest of the time working on my sim buddy, golden gate bridge fly-unders, 100 kt XW landings, etc, etc. But even so, the E-175 training is pretty easy or so I hear. I'd probably avoid anything like a Q400.
I would complete IOE, get some major airline interview prep, and then apply to all majors you're interested in. Keep in mind that you'll need to update each app every month or two, which is a lot of work. You'll also need to stay in the books, because you might get a short notice interview call, even without TPIC. More likely you'll need a couple thousand TPIC, but it could happen at any moment, hard to predict since it depends on your whole person package, training history, and background.
If you want a ULCC, that could happen within months.
Try to get your records from Endeavor, they are Pinnacle's successor. The good news is that nobody is likely to question your flight time during a period that you worked for an airline.
Also be prepared to explain to a major why you left aviation, and why things are different for you now. "I hated being away from home" is probably not the answer they're looking for.