I can tell you as someone who spent 6 years at TSA that you’re looking at this the wrong way and my opinion is based off of how you ask your question. I wouldn’t say you should ever look at a regional specifically and ask why should/shouldn’t I. That’s really the backwards way of going about deciding on a regional.

You really need to ask YOURSELF what you want out of this. What are YOUR priorities? Are you wanting to spend your entire career at a regional? If not do you want to go to a major? How do you want to get there? Do you want a flow? Do you want to hop around from regional to LCC to Major? Do you want to fly shiny new jets with engines that hang under the wing? What do you value? It sounds like no commuting so that’s a start (and a very wise start at that). Trans States will offer you damn near what any of these other regionals will. The regionals have all had to really compete heavily for the small pool of qualified candidates remaining which means that, barring signing bonuses at some and flow programs at others, you’ll get pretty much a very similar experience. A lot of flying in airplanes all over the country. My experience I had with the regionals and TSA taught me to really evaluate what you want and pick the one that checks the most boxes. Don’t look at any regional specifically and ask why. That’s my take anyways. Also don’t ever evaluate based on anything based in future speak. New planes, new bases etc. at the regional level they’ll never come and they’ll open and close at the drop of a hat.