There’s really a lot that goes into determining if it’s easier to drive or fly. You said you have three flights a day, and that’s pretty parallel to my situation.
Four hours is a long drive, but with only three flights a day there is a good chance you’ll spend more time than that waiting on a flight. I don’t think I’d be up for a drive that long week in week out, but I’d do it often.
There really is a lot to be said for your own car... you always have a seat and it leaves when you do every time.