I'm in the middle of selling a house and moving my wife and I someplace I never thought I'd even consider living, solely to not have a commute anymore.
I currently commute 2 short legs out of a town which has only 3 off line flights a day. This causes me to have to leave a day early and come home a day late most of the time (even with a 1200 show, do to only having 1 option). If I can't get on a flight it's a 1.5 hour drive to the next option with 2 flights a day, non-stop.
Everyone has a different tolerance to commuting, but for me it made me the first year of my "dream job" miserable. I am constantly stressing over and checking flight loads when I'm at home, which makes it hard to enjoy being there. I'm all about qol and it seems like I had none. I am still on reserve and couldn't even try to bid long call because I wouldn't have been able to get to base in 12 hours if called out in the evening.