Taking an RJ course may help you with the motions of sim training at a regional, but what about when you get to IOE? Sim training is like a "ballet", with choriographed (sp?) steps, that if followed, will result in a successful checkride. When you get turned loose for IOE, is that "transition" course going to help you fly into PHL, EWR, LGA, BOS, Etc? It takes real world experience to be able to fly into these types of airports, and none of the above will allow you to fly the "ballet" profile of a simulator on an approach. I have talked to many IOE CA's, and the stories used to be who got signed off in the quickest amount of time, now it is "wow I only had to take the airplane 3 times from this guy today."

My 2 cents is if you want to have the best success at making it to the line, go out and fly an actual airplane. Get your CFI, fly into some busy airports, and get comfortable with the real world IFR flying that you will be doing as a 121 line pilot. Passing sim training is only 1 part of your training process, you still will have to demonstrate your ability online in IOE, and only ACTUAL EXPERIENCE will help you with that.