My 2 cents are this. They can put a rover on Mars, so of course they could replace two pilots. But there’s way too much liability to do that right now. I mean, look at Space X. We have rockets that can land themselves, but what happens when there is an emergency? Those rockets sink to the bottom of the ocean. The same could happen with a fully automated aircraft. I’m sure it could fly flawlessly in standard conditions, but as soon as there is a “nonstandard” emergency the AI would crash. Plus you would have to keep in mind around the same time that there will most likely be other planes being hand flown, or at least wouldn’t be fully automated. So there would be a risk there as well, since you wouldn’t be able talk to a AI, it would just run its program until it landed. In short, I think the tech is possible but it would take years to get approved and implemented.