After 1.5-2 years, SDF-based pilots on the Bus or 757 can frequently hold majority day flying. Those lines generally are not super commuter-friendly, though some trips have commercial deadheads.
You could also bid international; no idea how ONT schedules at that longevity look.
UPS is currently hiring for growth airframes, as well as retiring at least double what mandatory retirements are.
Express freight isn’t for everybody, but even within a given fleet/seat/domicile there is significant diversity in trips/schedules so most can find something that suits their physical and QOL needs.