I did the DC to NYC commute for a year. Super easy, especially from DCA. The flights are on regionals, so you can’t reserve jumpseats, but the jumpseat is often open and they are shuttles so there are often open seats (I rarely had an issue, only on big weather days). And if you’re in the 220 or 717, you’ll be senior very quickly and your schedule becomes very controllable, including the ability to green slip. And depending on where exactly you live, driving to work is a backup option (mainly for EWR trips), which takes a lot of stress off commuting.