My wife is a nurse and I am a commuter. It is extremely hard on the family with her working and our new born. The ONLY way we can make it work with her working still is because we have my parents and her parents nearby as a support system. If you don't have this set up ahead of time it will not work out. Being a commuter pilot, he will be gone for long chunks of time and you be stuck to deal with the rest at home.