Really sorry to hear that. Tough question to answer because of so many variables.

How Old, which airline, your past, family situation, commuter etc. I mean if I was 50 and just furloughed I would be thinking really hard about spending the next 15 years at a regional, especially if I dont live in base. That said, if I was 25, single and living in my parents house still, I would ride this out and do something else for a year or so. Everyone in between, (that's me), well we have some tough choices ahead of us that's for sure. The airlines will hire again, its just a matter of time.