Originally Posted by
Excargodog
Here is the peer reviewed article in the international journal of infectious diseases.
https://www.ijidonline.com/article/S...534-8/fulltext
And obviously some of the findings are contradictory and no doubt additional studies are even now underway to resolve that, but as far as cardiac toxicity of hydroxychloroquine and chloroquine, people should understand that until the rise of chloroquine resistant malaria, these drugs were mainstays of the WHO malaria control program and routinely taken by 100s of millions of people in malaria us areas for decades. While cardiac toxicity can and does occur, it did not occur with such frequency as to contraindicated its routine use in these areas.
https://www.ncbi.nlm.nih.gov/books/NBK2616/
https://pubmed.ncbi.nlm.nih.gov/29858838/
These drugs are still routinely used for medical indications far less threatening than being hospitalized In an ICU for COVID 19.
Whether they actually ARE effective will probably require further testing to confirm or refute, but both Aralen (chloroquine) and Plaquenil (hydroxy chloroquine) are FDA approved drugs widely prescribed for rheumatoid arthritis and antimalarial treatment worldwide.
Sure and most of those studies have been finished. This study was observational and thus does not have a double blind control group. It makes the study interesting but stacked up against double blind studies doesn’t pull much weight. I would find its politics suspect even if the trails were held in the US. That said it failed in six countries for hospitalized patients so it is ok to move on. Multiple drugs have failed in this setting. It’s ok they weren’t designed for it.