Originally Posted by
OpMidClimax
At this time there is no evidence of latency. Yes a decade later this could be proven different. But, with this genome, it's just not predicted. None of the colleagues I work with are tuned to this. We are all in agreement of reinfection vs relapse at the moment.
Dr.
Muhammad Yousuf highlights the summary below.
Current clinical evidence is highly in the two articles. Note in the first article (1) that HCWs who had clinical recovery did not transmit the disease to contacts despite positive RT-PCR tests.
Study (2), patients who had clinically recovered but showed positive RNA based RT-PCR tests did not transmit COVID-19 by donating plasma that was transfused to other recipients.
This indicates that SARS-CoV-2 virus latency or reactivation is more of a hype than a reality and viral RNA in clinically recovered patient is inactive viral litter or garbage, not an active virus.
1.
Article https://www.researchgate.net/publica..._February_2020
2.
Article https://www.researchgate.net/publica...ients_in_China
No evidence that people with herpes zoster - which is most of us - transmit it if we donate IGG either. I don’t know why you would consider that proof of anything. Yes, it’s an RNA virus and we haven’t seen that producing latency in humans (yet) but DNA viruses can be latent in other mammalian species and a coronavirus definitely can be latent in lab rats. Time will tell.