I don’t think that will prove to be much of an issue. Not even taking the placebo effect into consideration, it’s really only necessary for vulnerable populations to take it. That alone will basically eliminate the death rate. Even if only half of people over 70 take it, they have a high probability of dying of anything every year over 70. Everyone else will take it or not, and it will really only affect who gets sick and who doesn’t. As long as those vulnerable populations are taking it, people who don’t take it won’t really prevent moving the needle on the death rate.