Obviously, we aren’t going to wait 5, 10, 20 years. I’m likely going to be at the front of the line as an EMS provider, and I’m trying to figure out how safe the tech likely is before I raise my hand.
I know that mRNA tech has been used in cancer meds for a while, but this is its first foray into battling a pathogen. It makes a whole lot of sense—code a string of mRNA, inject it as a more stable form, let it break back down to mRNA, high five with some ribosomes and crap out proteins that will trigger a specific immune response. mRNA doesn’t last long, so it will degrade soon after translation.
I’m not a cellular biology expert, but it seems to me like the issue could be where the stabilized form of mRNA turns back into mRNA in the body? If that goes sideways, and the codons get f’d up, it could maybe result in the wrong/no polypeptide being created?
Just thinking aloud.