There’s plenty of actual evidence that shift work can shorten lifespans in the population at large.
That said, there’s no recent public data I’m aware of to show FDX/UPS pilots have shorter lifespans than passenger airline pilots. If there was, don’t you think it’d get a LOT of press and be used to help get cargo under 117 AND improve collective bargaining?
Lots of crew van rumors are “known” to be true when shared by pilots, with nothing concrete to back them up...