I Use the Bose Pro Flight Series 2 and am very happy with that. I tend to put it on early and have one earbud in for the radio and one out for internal discussions. When I was on the A320 it worked well to keep one in and one out when the other guy preferred to take his headset off. Its a bit pricey but I feel the noise cancelling makes the day less fatiguing. Downside form the QC25 or similar with a uflymike is that the pro elite really isn't going to allow you to detach the mic as easily and use it when on a DH.