777 at Purple vs Whale layovers at Brown being less may have something to do with a higher level of optimizer perhaps or maybe just customer base. Either way, doing your due diligence on how operations at various outfits may affect your life/lifestyle or health is in your court. Very good information provided by those flying the line at Brown. Whether its international, domestic, sort, etc., unless you have been thru it for some duration the only way is to try it and find out in the end if it works for you. Sounds like variety is offered so you have that going for you which is nice. On a side note as an ACMI flyer, I enjoy night and day or both types of flying with some very decent layovers. When it should be rough my only saving grace is the CPAP which does wonders specifically for me. Exercise is great along with eating right, but traveling to unique/great locations sometimes negates the correct method and I indulge in the local eateries. Like Boiler and others mentioned - be disciplined and the health aspect should be take care of itself. My other thought would be the 3 or 4 legs a night or day over and over again that would hurt me, while others would detest a long haul leg or two regardless of dozing for dollars. It’s in the eye of the beholder or as others have said a niche. Seniority is king, find your happy place.