I'm certain it doesn't help, but there are so many variables. I've done all kinds of bizzare schedules at airlines and in the military...some were tolerable, others not so much.

How many days per month?

Is it a consistent rythm, or all over the map?

Do you fly locals, where you return home each morning? That's bad because there's too much going on at home during the day...hard to sleep. I did this for a while, and actually observed myself aging faster.

The biggest factor would be your lifestyle...if you can live your entire life on the back side you should suffer no ill-effects (maybe a lack of vitamin D). But most pilots are into relationships and families, so that's kind of hard to pull off.