ACMI is a special lifestyle, if that's your gig you can make decent money down the road.

But in this climate there's no need for that sort of detour if your goal is top-tier pax airlines. Regional or LCC is the path of least resistance.

Alternatively if you're young, single, and adventurous then ACMI might be an interesting experience and with fast upgrade would probably offer the same time building as a regional. Make sure you know what the annual block hours will be though. Definitely good on the resume if FDX/UPS is your goal.