Holding a line at min days off and commuting sucks. I'm only doing it from STL-IND and I have a commuter clause to use. If I have only two days off I just stay in Indy. I'd never imagine doing it without one. Move to STL or wait for a western base at another regional. Your sanity will thank you.

On reserve at TSA or a line towards the bottom will guarantee you min days off. You may be able to trade some stuff around to get a better schedule but even that is a crapshoot. With that distance, and only a couple direct options (I think AA is the only with a couple nonstops) and that distance you're spending the majority of your days off trying to get home, and then back to work.