Ive been riding for decades and do a bunch of motorcycle touring every year, and have thought about riding to work. To me the issue just presented too many hassles for the reward. I’d think that a lot depends on the bike and the type of trip. There’s a big difference in packing for a trip when riding a touring bike vs a sport bike. Saddle bags and a trunk carry a lot of stuff and you can leave your helmet and protective gear locked in them once you get to the airport. Strapping a full sized roller board suitcase to any bike could obviously be problematic, but a nice soft side duffel bag could easily work. Some of the sport bikes these days come with small saddle bags and there is always after market trunk mounts that would work and could be quickly removed when not going to work. Givi makes a nice trunk that is very well priced if you don’t need to have your bike’s brand plastered all over everything that you own, cough cough Harley guys. Weather is always an issue, but rain gear can get you home, and if the weather is bad on the go to work day, just leave the bike in the garage. Mesh riding gear could easily cover your uniform while also providing protection. It’s very doable, but only you can decide if it’s worth it.