Originally Posted by
rickair7777
121 aviation generally is certified with a 10^-9 safety factor... they should probably start with that and work backwards from there. That's how they certify airplanes and operating procedures.
Well, yes and no. That safety factor (or as they say, extremely improbable) is used for failures where the result is catastrophic. Pilot incapacity in a two-pilot plane is not a catastrophic event, and thus does not need to be certified to that standard.