Yeah pursue all top tier jobs which you'd be willing to accept. Unless commuting is intolerable to you and you need to live in a specific domicile.
Give that some time (months? one year?) and then apply to all second-tier you'd be willing to accept. I suggest the delay because there's a good chance you'll get called immediately, which you might not want to do until you throw your hat in the top tier ring for at least a while. Although second-tier hiring might be slowing a bit.