I live in Petaluma and the worst time to have to drive in starts about 6:30am or so. So for an earlier show I try to be out the door by about 6 and just accept I'll have plenty of time to grab a coffee. Then by about 9 it's not too bad. Coming home and being on the road between 3-6/6:30pm is pretty bad as well. So to commute from Sonoma County will largely depend on how many times a week the OP's wife has to go into SF and what time that is. WorstPilotEver isn't wrong in saying if her hours are about 5-1 it's fine.